Le Zhang
Education Background
2011-present Managing Director, the Editorial Board of Chinese Journal of Reproductive Health
2006-present Assistant Professor, Institute of Reproductive and Child Health, Peking University, Beijing, P. R. China
2003-2006 Ph.D. in Epidemiology, School of Public Health, Peking University Health Science Center
2001-2003 M.S. in Epidemiology, School of Public Health, Peking University Health Science Center.
1997- 2001 Public Health Physician, Baotou Institute of Health, Baotou, P. R. China
1992-1997 B.S. in School of Health Care Management, Beijing University of Chinese Medicine.
Overall introduction
My work is to use multidisciplinary methods such as epidemiology, nutrition/environmental health, and data science to reveal the effects and mechanisms of environmental pollution exposure and nutritional imbalance on reproductive health. I have presided 3 sub-projects from provincial key r&d and achievements transformation program in China as the principal investigator, and participated in 1 National Key R&D Projects and 1 National Natural Science Foundation of China (NSFC) as backbone member. As the first or corresponding author, I have published a total of nearly 20 papers in international or Chinese authoritative journals. I participate in teaching the undergraduate course "Introduction to Birth Defects" and PBL course. I won the Second Prize of Science and Technology of Beijing Preventive Medicine Association.
Main research directions
Environment Health, Nutrition，Birth defects and other adverse pregnancy outcomes , Pregnancy complications
Representative scientific research projects
| (1) | Key R&D and Achievements Transformation Program of Tibet Autonomous Region. Le Zhang(co-PI). Development of key technologies for early diagnosis and treatment of maternal and fetal cardiovascular disease and construction of prediction model in plateau area, 2024-2026, co-Principal Investigator,Ongoing. |
| (2) | Key R&D and Achievements Transformation Program of Inner Mongolia Autonomous Region’s 14 th Five-Year Plan Period, 2023YFSH0048, Survey on prevalence of vaginal laxity syndrome in Inner Mongolia] Autonomous Region, development and application of stromal vascular fraction technology to treat VLS, 2023-2026,co-Principal Investigator,Ongoing. |
| (3) | Key R&D and Achievements Transformation Program of Inner Mongolia Autonomous Region’s 14 th Five-Year Plan Period, 2023YFSH0051, ldentification of serological and metabonomic biomarkers, development and application of early predictive model for spontaneous preterm birth. 2023-2026, co-Principal Investigator,Ongoing. |
| (4) | China’s Natural Science Foundation (No:82173527), Study on the association and their mechanisms between exposure to rare earth elements during pregnancy and the risk of hypertensive disorders of pregnancy, 2022-2025, Backbone Member, Ongoing. |
| (5) | Data mining on preimplantation genetic testing data, 2021-2025, Principal Investigator, Ongoing. |
| (6) | National Key Research and Development Program, 2020YFC0846300, Study on the Epidemiological Characteristics and Evaluation of Prevention and Control Strategies of the COVID-19 Spreading, 2020/04-2021/04, Backbone Member, Completed. |
10 representative papers
| (1) | Min Li, Le Zhang*, Lu Gan*, Zhiwen Li. The Impact of Pregnancy Termination before 28 Weeks of Gestation on the Overall Prevalence of Birth Defects — Shaanxi Province, China, 2014–2020[J]. China CDC Weekly, 2022, 4(43): 967-973. doi: 10.46234/ccdcw2022.197 |
| (2) | Yushan Du, Shuangbo Xia, Jinjuan Zhang, Le Zhang*, Jufen Liu*. Plasma folate deficiency increases the risk for abnormal blood pressure in Chinese women of childbearing age. Nutrition Research, 2021, https://doi.org/10.1016/j.nutres.2021.12.003. |
| (3) | Jia X, Zhang L#, Zhao J, Ren M, Li Z, Wang J, Wang S, Liu Y, An H, Li Y, Yan L, Li Z*, Liu X*, Pan B*, Ye R. Associations between endocrine-disrupting heavy metals in maternal hair and gestational diabetes mellitus: A nested case-control study in China. Environ Int. 2021 Dec;157:106770. doi: 10.1016/j.envint.2021.106770. Epub 2021 Jul 24. PMID: 34314978. |
| (4) | Song Q, Wei J, Wang J, Zhang L*, Liu X*, Zhang Y, Li N, Li Z. Rate of Correct Use of Folic Acid Supplementation Among Pregnant Women - Beijing Municipality, China, 2017-2019. China CDC Wkly. 2021 Sep 10;3(37):783-787. |
| (5) | Xiaoqian Jia, Mengyuan Ren, Yali Zhang, Rongwei Ye, Le Zhang *, Zhiwen Li*. Association between tea drinking and plasma folate concentration among women aged 18-30 years in China. Public Health Nutrition: 4929-4936. |
| (6) | Zhang L, Zhang Y#, Li Z*, Ren A, Liu J, Ye R*. Maternal periconceptional body mass index and risk for neural tube defects: results from a large cohort study in China. J Matern Fetal Neonatal Med. 2021 Jan;34(2):274-280. |
| (7) | Yongxiu Hao, Yiming Pang, Huina Yan, Yali Zhang, Jufen Liu, Lei Jin, Lailai Yan, Da Chen, Ligang Hu, Qian Liu, Yanan Qin, Bin Wang, Zhiwen Li, Rongwei Ye *, Le Zhang*, Aiguo Ren, Association of maternal serum copper during early pregnancy with the risk of spontaneous preterm birth: a nested case-control study in China, Environ Int, 2019,122:237-243. |
| (8) | YAN Hui-na, WANG Zhan, WANG Jia-mei, LlU Xiao-hong, ZHANG Le *.Survey on caffeine exposure among pregnant women in high intellectual area of Beijing.Chinese Journal of Health Education,2017,33(11):1005-1007,1015. |
| (9) | MENG Fanwen, CHEN Sen, LIU Yashan,LI Nan, YANG Na, LIU Yingjuan, ZHANG Le*, YE Rongwei*. Incidence and risk factors of hypertensive disorders complicating pregnancy in 5 counties of Hebei province. Chinese Journal of Reproductive Health, 2015, 26(2): 112-115. |
| (10) | ZHANG Le, SUN Mei-Ping, GAO Wei-Xian, HONG Shi-Xin, ZHANG Ya-Li*. Prenatal screening for major fetal heart defects by training sonographers in township hospitals and county health centers: a feasibility study[J]. Journal of Peking University(Health Sciences), 2014, 46(3): 373-378. |
Note：*Corresponding author, #Co-first author