Weidong Hao

Personal profile

Personal profile

08/2001- present Professor and Chairman, Department of Toxicology, Vice Dean, School of Public Health, Peking University

06/1996-08/2001 Associate Professor and Vice Chairman, Department of Toxicology, Beijing Medical University

09/1990-09/1991 and 04/1995-04/1996 Visiting Scholar, Faculty of Pharmaceutical Sciences, Okayama University, Japan

05/1990-05/1996 Lecturer, Department of Toxicology, Beijing Medical University

08/1987-05/1990 Assistant, Department of Toxicology, Beijing Medical University

08/1984-08/1987 Department of Toxicology, Beijing Medical University, Got Master of Medicine degree in August 1987

09/1979-08/1984 School of Public Health, Beijing Medical University, Got Bachelor of Medicine degree in August 1984


Academic Positions:

Vice Chairman and Secretary General, Chinese Environmental Mutagen Society

Council Member, International Association of Environmental Mutagen and Genomic Societies

Member, Executive Committee of Asia Association of Environmental Mutagen Society

Member, Executive Council of Chinese Association of Preventive Medicine

Member, Executive Council of Chinese Toxicology Association

Vice Chairman, The Society of Environment and Health, Chinese Society of Environmental Science

Vice Chairman, The Society of Biological Chemical and Molecular Toxicology, Chinese Toxicology Association

Vice Chairman, The Society of Toxicological Alternatives and Translational Toxicology, Chinese Toxicology Association

Vice Chairman, The Society of Toxicity Testing and Alternative Methods, Chinese Environmental Mutagen Society

Associate Editor of Chinese Preventive Medicine (Chinese)

Associate Editor of Carcinogenesis, Teratogenesis & Mutagenesis (Chinese)

Main research directions

Food Toxicology and Environmental Toxicology

Representative scientific research projects

  1. The National Key Research and Development Program of China, 2017YFC1600203, Safety evaluation of rare earth elements and additives in food based on toxic mechanism and health effect endpoints, 2018/01-2021/12, PI

  2. National Natural Science Foundation of China, 82073586, Effect of 2-acetyl-4-tetrahydroxybutylimidazole on lymphocyte reduction and its mechanism, 2021/01-2024/12, PI

  3. National Natural Science Foundation of China, 81773466, Study of reproductive toxicity by chlormequat chloride and its potential mechanism of impact testosterone synthesis through HPG axis, 2018/01-2021/12, PI

  4. National Natural Science Foundation of China, 81473002, Study of embryotoxicity by chlormequat chloride and its potential mechanism through GH-IGF regulation axis, 2015/01-2018/12, PI

  5. National Natural Science Foundation of China, 81273112, Effect of TAK1 mediated CD4(+) T cell activation on allergic contact dermatitis and auto immune hepatitis induced by trichloroethylene, 2013/01-2016/12, PI

  6. National Natural Science Foundation of China, 30972501, Effect of signal transduction and epigenetic on neurodevelopmental toxicity by bisphenol A,  2010/01-2012/12, PI

  7. National Natural Science Foundation of China, 30771821, Interaction and mechanism of developmental toxicity of phtoestrogens and synthetic chemicals, 2008/01-2010/12,PI

  8. National Natural Science Foundation of China, 39600123, Molecular mechanism of gene mutation induced by sunlight and ultraviolet radiation, 1997/01-1999/12, PI

10 representative papers

  1. Qianqian Xiao, Xiaohong Hou, Chenping Kang, Linglu Xu, Lilan Yuan, Zhe Zhao, Qinghe Meng, Jianjun Jiang, Weidong Hao*, Chlorocholine chloride induced testosterone secretion inhibition mediated by endoplasmic reticulum stress in primary rat Leydig cells,Toxicology Letters, 2021, 356 :161–171.

  2. Qianqian Xiao, Xiaohong Hou, Chenping Kang, Bayindala Xiagedeer , Hong Hu , Qinghe Meng , Jianjun Jiang, Weidong Hao*, Effects of prenatal chlorocholine chloride exposure on pubertal development and reproduction of male offspring in rats, Toxicology Letters, 2021, 351 :28–36.

  3. Bayindala Xiagedeer, Xiaohong Hou, Qi Zhang, Hong Hu, Chenping Kang, Qianqian Xiao, WeidongHao*, Maternal chlormequat chloride exposure disrupts embryonic growth and produces postnatal adverse effects, Toxicology, 2020, 442:152534.

  4. Xiaohong Hou, Hong Hu, Bayindala Xiagedeer, Pengmin Wang, Chenping Kang, Qi Zhang, Qinghe Meng, Weidong Hao*. Effects of chlorocholine chloride on pubertal development and reproductive functions in male rats, Toxicology Letters,  2020, 319:1-10.

  5. Bayindala Xiagedeer, Chenping Kang, Xiaohong Hou, Hong Hu, Qianqian Xiao, Weidong Hao*, Chlormequat chloride promotes rat embryonic growth and GH-IGF-1 axis, Toxicology,429:1-9.

  6. Yao Pan, Xiaohong Hou, Qinghe Meng, Xiaohua Yang, Lanqin Shang,  XuetaoWei, Weidong Hao*, The critical role for TAK1 in trichloroethylene-induced contact hypersensitivity in vivo and in CD4+ T cell function alteration by trichloroethylene and its metabolites in vitro,Toxicology and Applied Pharmacology,2019,381:1-14.

  7. Xiaohong Hou, Dan Huang, Qinghe Meng, Qi Zhang, Lixia Jia, Siqi Wang, Zhiyuan Cheng, Shuang Wu, Lanqin Shang, Jianjun Jiang, Weidong Hao*, Pubertal chlorocholine chloride exposure inhibits testicular testosterone synthesis by down-regulating  steroidogenic enzymes,Toxicology Letters, 2018, 288:17-24.

  8. Dan Huang, Shuang Wu, Xiaohong Hou, Lixia Jia, Qinghe Meng, Hongqian Chu, Jianjun Jiang, Lanqin Shang, Weidong Hao*, The Skeletal developmental toxicity of chlormequat chloride and its underlying mechanisms, Toxicology, 2017, 381:1-9.

  9. Hongqian Chu, Jing Shang, Ming Jin, Yueyue Chen, Yao Pan, Yuan Li, Xi Tao, Zhiyuan Cheng, Qinghe Me, Qian Li, Guang Jia, Tong Zhu, Weidong Hao*, Xuetao Wei*, Comparison of lung damage in mice exposed to black carbon particles and 1,4-naphthoquinone coated black carbon particles, Science of the Total Environment, 2017, 580:572-581.

  10. Hongqian Chu, Jing Shang,Ming Jin, Qian Li, Yueyue Chen, Hongpeng Huang, Yuan Li, Yao Pan, Xi Tao, Zhiyuan Cheng, Qinghe Meng, Guang Jia, Tong Zhu, Xuetao Wei*, Weidong Hao*, Comparison of lung damage in mice exposed to black carbon particles and ozone-oxidized black carbon particles, Science of the Total Environment, 2016, 573:303-312.