My main interest is to adopt multidisciplinary study methods such as epidemiology, toxicology, multi-omics and environmental health, to claim the effect and mechanism of exogenous environmental and chemical factors on embryo development, as well as to explore intervention strategy on health damages. I am proficient in using animal exposure models to study the mechanisms of perinatal complications, to evaluate the embryonic toxicity of environmental chemicals. And I have mastered 16sRNA sequence analysis of gut microbiota and metabolomics research methods. In addition, mixed exposure factor scores are constructed based on large prospective cohorts to explore early-life risk factors and their long-term health effects. As the first or corresponding author, I have published eight papers in environmental chemical and nutritional journals, e.g., Ecotoxicol Environ Saf, Diabetes Res Clin Pract and Chem Biol Interact. I have presided two projects from China Postdoctoral Science Foundation and Beijing Natural Science Foundation as the principal investigator. With spatial metabolomics technology, the projects aim to deeply study the role of mechanism-inflammation network in preeclampsia mechanism, and to explore safe and effective invention strategy and early biomarkers via combining three-dimensional vitro model and vivo model. Our studies are helpful in improving the health of mother and fetus during perinatal period, as well as strengthening disease risk prediction.

Environment Health, Reproductive Toxicology