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闫赖赖

闫赖赖
助理研究员
  • 邮箱:yll@bjmu.edu.cn
  • 地址:北京市海淀区学院路38号

教育经历

08/2011至今           北京大学,公共卫生学院卫生检验学系,助理研究员

09/2009~08/2011  北京大学,公共卫生学院卫生检验学系,初级研究员

09/2012~01/2017 北京大学,公共卫生学院,博士

09/2006~07/2009 北京大学,公共卫生学院,硕士

09/2001~07/2006 山西医科大学,公共卫生学院,学士

教学科研简介

采用卫生化学、流行病学、临床医学、生物信息学等多学科研究方法,通过分析生物样本中金属元素含量来阐明金属元素暴露与人体健康的关系及可能机制。作为骨干参与2项国家重点研发项目;作为合作单位,参与国家自然科学基金-地区科学基金项目。以第一或通讯作者在Journal of hazard materials、Environment International、Science of the total environment、 Environmental Pollution等国际权威期刊发表论文20余篇。现担任原子光谱应用与技术专业委员会委员,北京金属组学平台副秘书长。曾参与讲授的课程有科研仪器实验技能、高级医药卫生仪器分析、高级医学技术以及公卫学院PBL实验教学。2020年获得北京大学第二十届青年教师教学基本功比赛(医科类)二等奖和公共卫生学一等奖。

主要研究方向

金属组学与人体健康的关系;仪器分析在公共卫生领域中的应用

代表性科研项目

  1. 典型区域大气污染健康影响评估与应用示范,国家科技部重点研发计划,基金号:2023YFC3708305,课题4:大气污染致病的全链条追因及疾病负担评价研究,子课题:大气污染对典型高发疾病的疾病负担评价,2023/12-2027/11,89万元,子课题负责人/骨干,在研

  2. 典型新兴农用化学品的暴露特征及其生殖健康风险评估. 科技部政府间国际科技创新合作(中国和美国),基金号:2022YFE0134900,课题1“典型新兴农用化学品的暴露特征及其与生殖健康效应的关联性”,2023/01-2025/12,20万元,子课题负责人/骨干,在研

  3. 国家自然科学基金-地区科学基金项目,82060600,白云鄂博矿区轻稀土暴露与小于胎龄儿的相关性研究,2021-01至2024-12,40.1万元,合作单位负责人,在研

  4. 北京大学医学交叉种子基金,BMU2017MX006,基于血浆金属组学和氨基酸代谢组学的首发精神分裂症研究,2018/01-2018/12,已结题,主持

10篇代表性论文

  1. Minghao Wang#, Lailai Yan#, Siqi Dou#, Liu Yang, Yiwen Zhang, Wenzhong Huang, Shanshan Li, Peng Lu*, Yuming Guo*, Blood multiple heavy metals exposure and lung function in young adults: A prospective Cohort study in China, Journal of Hazardous Materials,459(2023)132064.

  2. Bing Cao#*, Ruiqi Wang#, Angela T.H. Kwan, Roger S. McIntyre , Lailai Yan* Association between rare earth elements and depression: Evidence from pilot mice model of chronic unpredictable mild stress-induced depression and human studies of major depressive disorder, Chemosphere, 345 (2023) 140525.

  3. Weiling Han , Wei Zheng , AiliWang , Junxi Chen , JiaWang, Junhua Huang, Hang An Yuru Ma, Kexin Zhang, Ruihua Yang, Lailai Yan*, Zhiwen Li and Guanghui Li* Association of Maternal Plasma Manganese with the Risk of Spontaneous Preterm Birth: A Nested Case–Control Study Based on the Beijing Birth Cohort Study (BBCS) in China, Nutrients, 2023,15(6),1413.

  4. Gongbo Chen#, Jiping Tan#, Lailai Yan#, Nan Li, Luning Wang, Na Li, Lei Mai, Yiming Zhao, Shanshan Li,Yuming Guo Long-term exposures to ambient PM1 and NO2 pollution in relation to mild cognitive impairment of male veterans in China. Environmental Research Letters,2021,16(2),025013

  5. Mengyuan Ren#, Lailai Yan#, Yiming Pang, Xiaoqian Jia, Jing Huang , Guofeng Shen, Hefa Cheng, Xilong Wang, Bo Pan, Zhiwen Li, Bin Wang. External interference from ambient air pollution on using hair metal(loid)s for biomarker-based exposure assessment. Environment International, 2020,137,105584.

  6. Yongxiu Hao#, Lailai Yan#, Yiming Pang, Huina Yan, Le Zhang, Jufen Liu, Nan Li, Bin Wang, Yali Zhang* , Zhiwen Li, Rongwei Ye, Aiguo Ren. Maternal serum level of manganese, single nucleotide polymorphisms, and risk of spontaneous preterm birth: A nested case-control study in China. Environmental Pollution, 2020,262,114187.

  7. Yiming Pang#, Lailai Yan#, Mengyuan Ren, Xiaoqian Jia, Tanxin Liu, Wei Du, Bin Wang , Zhiwen Li*, Qun Lu*. Environmental complex exposure and the risk of influenza-like illness among housewives: A case study in Shanxi Province, China. Ecotoxicol Environ Saf.2020, 194:110405.

  8. Bing Cao, Yan Chen, Joshua D. Rosenbalt, Roger S. McIntyre, Dongliang Wang*, Lailai Yan*. Association of alkali metals and Alkaline-earth metals with the risk of schizophrenia in a Chinese population: A Case-Control study. Journal of Trace Elements in Medicine and Biology, 2020,60: 126478.

  9. Lailai Yan#, Juntuo Zhou#, Dong fang Wang, Dan dan Si,Ya qiong Liu,Li jun Zhong* Yuxin Yin*. Unbiased lipidomic profiling reveals metabolomic changes during the onset and antipsychotics treatment of schizophrenia disease, Metabolomics, 2018, 14(6):80.

  10. Lailai Yan#, Bin Wang#, Zhenjiang Li, Yaqiong Liu, Wenhua Huo, Jingyu Wang*, Zhiwen Li*, Aiguo Ren, Association of essential trace metals in maternal hair with the risk of neural tube defects in offspring, Birth Defects Research A, 2017, 109(3): 234-243.

说明:*通讯作者,#共同第一作者