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National level

Year 2025

  1. Bin Wang, National Natural Science Foundation of China (NSFC), No. 42477455, Constructing a Prediction Model for PFASs Concentration in the Blood and Follicular Fluid of Childbearing-age Women in the Regional Level Based on the Exposome Big Data, 2025/01-2028/12, 470,000 RMB, Principal Investigator

  2. Linlin Wang, National Natural Science Foundation of China (NSFC), No. ‪82473639, Prenatal exposure to organophosphorus flame retardants and the risk of neural tube defects, and the mechanisms of mitophagy and pyroptosis, 2025/01-2028/12, 490,000 RMB, Principal Investigator


    Year 2024

  3. Tao Xue, National Natural Science Foundation of China (NSFC), 42375179, New epidemiological method to identify the threshold of health effects of air pollution, 01/2024-12/2027, 510K, Principal Investigator, Ongoing

  4. Zhiwen Li, National Natural Science Foundation of China (NSFC), 82373582, The role of maternal CYP1 enzyme metabolic capacity, and BPDE-DNA adduct levels in maternal and offspring tissues in the occurrence of neural tube defects induced by benzo(a)pyrene, 2024/01-2027/12，490,000 RMB, Principal Investigator

  5. Zhiwen Li, National Natural Science Foundation of China-Joint Key project of Regional Innovation and Development, U23A20420, Research on important environment, genetic factors and pathogenic mechanism and early intervention of folic acid non-responsive neural tube defects in Shanxi, 2024/01-2027/12, 416,000 RMB, Key Investigator

  6. Jufen Liu, Key Project of Regional Innovative Development Joint Fund of National Natural Science Foundation of China, U23A20420, Research on Important Susceptibility Factors, Pathogenic Mechanisms, and Early Intervention Strategies of Folate Non-Responsive Neural Tube Defects, 2024/01-2028/12, 416,000 RMB, Subproject Leader/Core member, Ongoing


    Year 2023

  7. Li Hong-tian, Key National Research and Development Program of the Ministry of Science and Technology, 2023YFC2506800, Artificial Intelligence Monitoring and Diagnostic Technology and Platform Construction for Common Mental Disorders, 2023/11-2026/10, 600,000 RMB, Core Investigator

  8. Bin Wang, Typical Regional Atmospheric Pollution Health Impact Assessment and Application Demonstration, Key Research and Development Program of the Ministry of Science and Technology, No. 2023YFC3708305, Project 5: Comprehensive Attribution of Atmospheric Pollution-Induced Diseases and Assessment of Disease Burden, Subproject: Assessment of Human Internal Exposure and Integrated Analysis of Health Risks, 2023/12-2027/11, 360,000 RMB, Backbone member/ Sub-project Principal Investigator

  9. Bin Wang, Government-to-government international scientific and technological innovation cooperation project of Ministry of Science and Technology (China and the United States), No. 2022YFE0134900, "Exposure characteristics of typical emerging agricultural chemicals and their reproductive health risk assessment (2023-2025)," served as the Principal Investigator for Task 1 to undertake the study on "Exposure characteristics of typical emerging agricultural chemicals and their association with reproductive health effects.", 400,000 RMB, Backbone member/ Sub-project Principal Investigator


    Year 2022

  10. Jufen Liu, National Key Research and Development Program of Ministry of Science and Technology, 2022YFC2705205, Establishment of Early Diagnosis, Intervention, and Early Warning System for Common Developmental Behavioral Disorders in Children, 2022/01-2025/12, 600,000 RMB, Core member

  11. Jufen Liu, Major Project of National Social Science Foundation, 21&ZD187, Study on Disability Prevention Strategies and Applications under the Background of Population Aging, 2022/01-2025/12, 600,000 RMB, Core member

  12. Tao Xue, National Natural Science Foundation of China (NSFC), 42175182, Risk assessment of joint exposure to PM2.5, O3 and temperature based on a data-fusion machine learning model in China, 01/2022-12/2025, 550K, Principal Investigator, Ongoing

  13. Linlin Wang, National Key Research and Development Program of the Ministry of Science and Technology, 2022YFC2705205, Research on the Interaction Mechanism between Genetic and Risk Factors of Developmental Behavioral Diseases and the Establishment of an Early Warning System, December 2022 - November 2025, 1.6 million RMB, Sub-project Leader

  14. Liu Jianmeng, General Program of the National Natural Science Foundation of China, "Study on the Impact of Clamping Umbilical Cord Time During Cesarean Section on Neonatal Hemoglobin, Maternal Blood Loss, and Other Health Outcomes”, 2022/01-2025/12, 550,000 yuan, Principal Investigator

  15. Ye Rongwei, General Program of the National Natural Science Foundation of China, Research on the Relationship and Mechanism between Rare Earth Element Exposure during Pregnancy and the Risk of Hypertensive Disorders in Pregnancy, 2022/01-2025/12, Principal Investigator


    Year 2021

  16. Bin Wang, National Natural Science Foundation of China (NSFC), No. 42077390, Study on the Transfer Mechanism of Polycyclic Aromatic Hydrocarbons through the Blood-Follicular Barrier and the Influencing Factors among the Women of Childbearing Age, 2021/01-2024/12, 570,000 RMB, Principal Investigator

  17. Jufen Liu, National Key Research and Development Program of Ministry of Science and Technology, 2021YFC2701101, Systematic Identification of Pathogenic Mutations in Major Birth Defects, 2021/01-2024/12, 1,000,000 RMB, Core member

  18. Linlin Wang, Major Project of the National Social Science Foundation, 21&ZD187, Research on Prevention Strategies and Applications of Developmental Disabilities in the Context of Population Aging, December 2021 - November 2024, 60,000 RMB, Sub-project Leader

  19. Linlin Wang, National Key Research and Development Program of the Ministry of Science and Technology, 2021YFC2701101, Systematic Identification of Pathogenic Mutations in Major Birth Defects, December 2021 - November 2024, 1 million RMB (independent funding), Key Project Member

  20. Zhiwen Li, National Key Research and Development Program of China, 2021YFC2701001, The role of environmental and epigenetic changes in occurrence of structural birth defects and their pathogenic mechanisms, 2021/12-2024/11, Key Investigator

  21. Lei Jin, Key Research and Development Program of the Ministry of Science and Technology, No. 2021YFC2700704, Screening of biomarkers and molecular mechanism analysis on glucose and lipid metabolism interactions between mother and fetus, 2021/01-2024/12, 600,000 RMB, Key Investigator

  22. Lei Jin，National Social Science Foundation Major Project, No.21&ZD187, Research on Prevention Strategies and Applications of Developmental Disabilities in the Context of Population Aging, 2021/12 – 2024/12, 10000 RMB, Key Investigator

  23. Lei Jin, Key Research and Development Program of the Ministry of Science and Technology, No. 2021YFC2701001, The Role and Mechanisms of Environmental and Epigenetic Changes in the Development of Structural Birth Defects, 2021/12 – 2024/12, 680,000 RMB, Key Investigator


    Year 2020

  24. Jufen Liu, National Natural Science Foundation of China (NSFC), No.8197120639, Study on the Synergistic Effects and Toxic Mechanisms of Polycyclic Aromatic Hydrocarbons Compound Exposure Inducing Fetal Neural Tube Defects, 2020/01-2023/12, 550,000 RMB, Main Participant (Fourth), Responsible for Fieldwork, Laboratory Management, and Database Organization

  25. Zhiwen Li, Chinese National Key Research and Development Program- Emergency Project, 2020YFC0846300, Effects of prenatal COVID19 infection on pregnancy outcomes, 2020-2021, 670,000 RMB, Role: Principle Investigator.

  26. Nan Li, National Nature Science Foundation of China，81903327，The association of phthalates with hypertensive disorders of pregnancy and its potential mechanisms，2020/01-2022/12，210,000 RMB, PI

  27. Nan Li, National Key Research and Development Program of China，2020YFC0846300，Effect of novel coronavirus pneumonia epidemic on adverse pregnancy outcomes in pregnant women，2020/04-2021/04, 5,000,000 RMB, Core member

  28. Zhiwen Li, National Natural Science Foundation of China (NSFC), 81973056, Synergistic effect and toxicity mechanisms of combined exposure of polycyclic aromatic hydrocarbons on the fetal neural tube defects, 2020/01-2023/12，500,000 RMB, Principal Investigator

  29. Bin Wang, National Key Research and Development Program, P.R. China, No. 42077390, Study on the Epidemiological Characteristics and Evaluation of Prevention and Control Strategies of the COVID-19 Spreading, 2021/04-2022/01, 5,000,000 RMB, Backbone member


    Year 2019

  30. Yubo Zhou, National Natural Science Foundation of China (NSFC), No. 81801542, The influence of pre-pregnancy obesity and excessive weight gain during pregnancy on anemia in the offspring of elderly women, 2019/01-2021/12, 210,000 RMB, Principal Investigator

  31. Lei Jin, National Natural Science Foundation of China (NSFC)，No. 81801542，The effects of pre-pregnancy obesity and excessive weight gain during gestational period on risk of anemia among the offsprings of puerperants with advanced age, 2019/01-2021/12, 210000RMB, Investigator


    Year 2018

  32. Bin Wang, National Natural Science Foundation of China (NSFC), No. 41771527, Study on the External and Internal Exposure Levels of Polycyclic Aromatic Hydrocarbons among Childbearing-age Women in North China, 2018/01-2021/12, 630,000 RMB, Principal Investigator

  33. Jufen Liu, National Natural Science Foundation of China (NSFC), No.41771527, Study on In Vitro and In Vivo Exposure Levels of Polycyclic Aromatic Hydrocarbons in Childbearing Women in Typical Regions of North China, 2018/01-2021/12, 630,000 RMB, Main Participant (First), Responsible for Fieldwork, Laboratory Management, and Database Organization

  34. Jufen Liu, National Natural Science Foundation of China (NSFC), No.81773441, Study on the Relationship between Fetal Central Nervous Tissue Somatic Cell Mutations and Neural Tube Defects, 2018/01-2021/12, 600,000 RMB, Main Participant (Third), Responsible for Fieldwork and Part of Database Work

  35. Linlin Wang, General Program of the National Natural Science Foundation of China, 81773441, Research on the Relationship between Somatic Mutations in Fetal Central Nervous Tissue and Neural Tube Defects, January 2018 - December 2021, 600,000 RMB, Project Leader

  36. Li Hong-tian, National Natural Science Foundation of China Youth Project, Randomized Controlled Study on the Impact of Vaginal Seeding on Body Mass Index and Allergy Risk Index of Infants Born by Cesarean Section, 2018/01-2020/12, 200,000 RMB, Principal Investigator

  37. Lei Jin, Key Research and Development Program of the Ministry of Science and Technology, No. 2018YFC1004301，A cohort study on the impact of environmental and behavioral factors on embryonic development and pregnancy based on external exposure monitoring，2018/12–2021/12，700,000RMB，Key Investigator


    Year 2017

  38. Zhiwen Li, National Natural Science Foundation of China (NSFC), 81673177, The inductive effect and mechanisms of polycyclic aromatic hydrocarbons on spontaneous preterm births and the prevention of folic acid, 2017/01-2020/12，550,000 RMB, Principal Investigator


    Year 2016

  39. Linlin Wang, Ministry of Science and Technology National Key R&D Program, 2016YFC1000501, Critical Stages in the Developmental Abnormalities of Major Organs Caused by Environmental Factors, July 2016 - June 2021, Key Team Member

  40. Zhiwen Li, National Key Research and Development Program of China, 2016YFC1000501, Key mechanisms related to Environmental factors induced abnormal development , 2016/07-2021/06，Key Investigator

  41. Li Hong-tian, Key National Research and Development Program of the Ministry of Science and Technology, Research on Prevention and Treatment Strategies for Pregnancy Complications in Elderly Women, 2016/07-2021/06, 681,600 RMB, Core Investigator

  42. Lei Jin, Key Research and Development Program of the Ministry of Science and Technology, No. 2016YFC1000501，Key link in the abnormal development of important organs caused by environmental factors, 2016/06–2021/05，600,000RMB，Key Investigator

  43. Liu Jianmeng, Key Research and Development Program of the National Ministry of Science and Technology, "Research on prevention and treatment strategies for pregnancy complications in women of advanced age”, 2016/07-2020/12, 3,218,400 yuan, Project Leader

  44. Liu Jianmeng, General Program of the National Natural Science Foundation of China, "Randomized Controlled Study on the Relationship Between Umbilical Cord Blood Milking During Cesarean Section and Infant Iron Deficiency-Related Health Outcomes”, 2016/01-2019/12, 800,000 yuan, Principal Investigator

  45. Ye Rongwei, General Program of the National Natural Science Foundation of China, Data Management and Analysis for Early Childhood Development Intervention Evaluation Study, 2016/01-2017/12, 200,000 RMB, Principal Investigator


    Year 2015

  46. Bin Wang, National Natural Science Foundation of China (NSFC), 41401583, Urban-Rural Differences in Exposure to Fine Particulate Matter and Levels of Oxidative Stress Damage among Women of Childbearing Age, 2015/01-2017/12, 250,000 RMB, Principal Investigator

  47. Jufen Liu, National Natural Science Foundation of China (NSFC), No.81472987, Study on the Association between Rare Variants and Abnormal Methylation of PCP Pathway Related Genes and Anencephaly in Fetuses, 2015/01-2018/12, 850,000 RMB, Main Participant (Third)，Responsible for Fieldwork and Part of Database Work

  48. Linlin Wang, General Program of the National Natural Science Foundation of China, 81472987, Research on the Association between Rare Variants and Abnormal Methylation of PCP Pathway-related Genes and Fetal Anencephaly, January 2015 - December 2018, 850,000 RMB, Project Leader

  49. Zhiwen Li, National Natural Science Foundation of China (China-UK cooperation), 2015-2017, 81511130088, Environmental and genetic determinants of neural tube defects, 98,000 RMB, Principle Investigator


    Year 2014

  50. Zhiwen Li, National Natural Science Foundation of China (NSFC), 81373014, The effect of maternal passive smoking during early pregnancy on risk of neural tube defects in offspring and the potential mechanisms, 2014/01-2017/12, 700,000 RMB, Principal Investigator


    Year 2013

  51. Jufen Liu, National Natural Science Foundation of China, 81202265, Study on the Correlation between COMT and MTHFR Gene Polymorphisms and Plasma Protein Expression and Neural Tube Defects, 2013/01-2015/12, 230,000 RMB, Principal Investigator

  52. Linlin Wang, National Natural Science Foundation of China, Young Scientists Fund, 81202215, Study on the Association between Maternal Placental and Blood Folate Receptor Antibodies During Pregnancy and the Risk of Fetal Neural Tube Defects, January 2013 - December 2015, 230,000 RMB, Principal Investigator

  53. Lei Jin, National Natural Science Foundation of China (NSFC)，No. 81271507，Associations of oxytocin and arginine vasopressin with pathogenesis of autism in children, 2013/01-2016/12，100,000RMB，Key Investigator

  54. Liu Jianmeng, General Program of the National Natural Science Foundation of China, "Cohort Study on Cesarean Section Requested by Pregnant Women and Childhood Metabolic Syndrome”, 2013/01-2016/12, 900,000 yuan, Principal Investigator


    Year 2011

  55. Jufen Liu, National Natural Science Foundation of China (NSFC), No.31071315, Study on the Relationship between Polycyclic Aromatic Hydrocarbons and Its Metabolic Enzyme Gene Polymorphisms and the Risk of Fetal Neural Tube Defects, 2011/01-2013/12, 300,000 RMB, Responsible for Data Analysis

  56. Zhiwen Li, National Natural Science Foundation of China (NSFC), No.31071315, Study on the Relationship between Polycyclic Aromatic Hydrocarbons and Its Metabolic Enzyme Gene Polymorphisms and the Risk of Fetal Neural Tube Defects, 2011/01-2013/12, 300,000 RMB, Key Investigator

  57. Liu Jianmeng, General Program of the National Natural Science Foundation of China, "Follow-Up Observation and Study on Renal Damage Mechanism of Children with Kidney Stones Caused by Melamine-Contaminated Milk Powder”, 2011/01-2013/12, 360,000 yuan, Principal Investigator


    Year 2010

  58. Liu Jianmeng, Science popularization project of the National Natural Science Foundation of China, "B Vitamins – Guardians of Health in the 21st Century”, 2010/01-2011/12, 200,000 yuan, Principal Investigator


    Year 2009

  59. Liu Jianmeng, National Basic Research Program (973 Program) of the National Ministry of Science and Technology, "Integrated Information Resource Research for Women and Children's Health Cohorts”, 2009/12-2011/10, 3,800,000 yuan, Sub-project Leader


    Year 2008

  60. Jufen Liu, Major Research Program of China Population Health Development Planning "973" Project "Research on the Genetic and Environmental Interaction Mechanism of Major Birth Defects in Chinese Population", No.2007CB5119001, 2008/01-2012/12，Main Participant


    Year 2007

  61. Jufen Liu, National Natural Science Foundation of China (NSFC) IIASA Young Scientists Summer Program, No.70711140163, 06/2007-08/2007，Project Executor


    Year 2006

  62. Liu Jianmeng, General Program of the National Natural Science Foundation of China, "Experimental Study on the Prevention and Treatment of Elderly Cardiovascular Diseases with B Vitamins”, 2006/01-2008/12, 250,000 yuan, Principal Investigator


    Year 2005

  63. Liu Jianmeng, General Program of the National Natural Science Foundation of China, "Epidemiological Randomized, Controlled, and Double-Blind Experimental Study on Lowering Plasma Homocysteine and Improving Vascular Endothelial Function with Low-Dose B Vitamin Dietary Supplements”, 2005/01-2005/12, 80,000 yuan, Principal Investigator


    Year 2003

  64. Jufen Liu, Major Research Program of China Population Health Development Planning "973" Project "Research on the Genetic and Environmental Controllability of Birth Defects in Chinese Population" (No.2001CB5103), 2003/01-2007/01，Main Participant